Hexamidine Diisethionate, Antibacterial Agent(CAS 659-40-5)
Product Name: Hexamidine Diisethionate
Abbreviation: Hexamidine
INCI Name: Hexamidine Diisethionate
CAS No.: 659-40-5
Grade: Cosmetic Grade (High-End Antibacterial & Scalp Repair Special)
Purity: ≥99.0%
Appearance: White Fine Crystalline Powder, Odorless
Molecular Formula: C₂₀H₂₆N₄O₂·2C₂H₆O₄S
Molecular Weight: 606.71
MOQ (Minimum Order Quantity): 1KG
Solubility: Easily soluble in water, glycerin and propylene glycol, the aqueous solution is clear and transparent without precipitation or stratification, insoluble in oil-phase solvents, with excellent water-phase dispersion and formula stability
Core Efficacy: Broad-spectrum efficient antibacterial, targeted inhibition of pathogenic bacteria on skin and scalp, rapid anti-inflammatory and redness relief, improve scalp itching and dandruff, regulate oil secretion, soothe sensitive skin, assist in acne repair
Key Characteristics: EU-approved safe cosmetic antibacterial ingredient, broad bacteriostatic spectrum, low dosage and high efficiency, mild non-irritating, no drug resistance, stable high temperature and light resistance, compatible with skin and scalp care systems
Storage Condition: Sealed, dry, cool and ventilated environment, avoid high temperature, strong light and humid storage conditions to prevent moisture agglomeration and efficacy attenuation, keep tightly sealed after opening
Shelf Life: 24 Months
Application: Widely used in anti-dandruff scalp care products, oil-control anti-acne essence, soothing repair lotion, facial cleanser, body care antibacterial products and daily mild antibacterial skin care formulas
Hexamidine Diisethionate, Antibacterial Agent, Anti-Inflammatory, Anti-Dandruff, Oil Control, Acne Treatment, Soothing Repair, Scalp Care, Cosmetic Grade Raw Material
Hexamidine Diisethionate, Antibacterial Agent(CAS 659-40-5)
Cosmetic-grade Hexamidine Diisethionate is a high-efficiency broad-spectrum antibacterial and anti-inflammatory active ingredient specially used for skin and scalp care, officially approved and widely recognized in EU cosmetic regulations. Different from traditional irritating antibacterial preservatives, Hexamidine Diisethionate features mild efficacy, high safety and broad bacteriostatic spectrum.
It can precisely inhibit the activity of various harmful microorganisms such as Propionibacterium acnes, Malassezia and Staphylococcus aureus on the skin and scalp, fundamentally solving skin problems caused by bacterial reproduction. On the scalp, it can effectively inhibit Malassezia proliferation, reduce scalp inflammation, relieve itching, cut off dandruff production from the source, and improve oily, itchy and flaky scalp.
For facial skin, it can suppress inflammatory acne, relieve redness and swelling of acne, regulate skin oil balance, and assist in repairing acne-prone skin. With stable water-phase performance, high temperature and light resistance, no irritation and no sensitization, no drug resistance after long-term use, it is a core mild antibacterial raw material for developing high-quality anti-dandruff scalp care, oil-control acne removal and soothing antibacterial skin care products.
Key Benefits
• Broad-Spectrum High-Efficiency Bacteriostasis: Effectively inhibit Malassezia, Propionibacterium acnes, Staphylococcus aureus and other pathogenic bacteria, solve dandruff, scalp itching and inflammatory acne problems in all directions.
• Mild & Low-Irritation High Safety: Officially certified by EU cosmetics regulations, mild and skin-friendly, no stimulation to scalp and facial skin, no sensitization, suitable for long-term daily care.
• Anti-Inflammatory & Itch-Relieving Rapid Repair: Quickly soothe skin and scalp inflammatory redness and itching, reduce inflammatory reactions, and accelerate subtle skin damage repair.
• Oil Control & Balance Sebum: Regulate scalp and facial sebum secretion, improve oily greasy state, prevent pore blockage and bacterial recurrence, and maintain refreshing skin and scalp state.
• No Drug Resistance & Stable Efficacy: Unique bacteriostatic mechanism will not induce microbial drug resistance, long-term stable efficacy, suitable for long-term repeated use of care products.
• Excellent Formula Stability: High temperature resistant and light resistant, stable in wide pH range, no discoloration or inactivation during production and storage, easy for industrial mass production and formula compounding.
Applications
• Anti-Dandruff & Scalp Care Products: Core active ingredient for high-end anti-dandruff shampoo and scalp essence, inhibit Malassezia growth, relieve scalp itching and redness, remove dandruff and improve oily scalp.
• Oil-Control & Anti-Acne Skin Care Series: Applied in anti-acne essence, toner and facial cleanser, inhibit acne bacteria reproduction, reduce inflammatory acne swelling, improve oily acne-prone skin.
• Mild Soothing & Antibacterial Products: Added in sensitive skin soothing lotion and repair serum, relieve skin inflammatory redness, stabilize skin microecology, and enhance skin tolerance.
• Body Antibacterial & Itch-Relieving Care: Suitable for body wash and body care formulas, inhibit body surface harmful bacteria, relieve body itching and follicular inflammation, and keep skin clean and healthy.
• Daily Mild Cleaning Products: Compounded in mild facial cleanser and daily cleaning products, achieve mild antibacterial and clean skin, prevent bacterial recurrence and maintain skin health.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Hexamidine Diisethionate | Compliant |
CAS No. | 659-40-5 | Compliant |
Appearance | White Fine Crystalline Powder, Odorless | Compliant |
Purity | ≥99.0% | 99.58% |
Water Solubility | Easily soluble in water, clear solution | Qualified |
Loss on Drying | ≤0.5% | 0.11% |
pH Value (1% Aqueous Solution) | 5.5-7.5 | 6.3 |
Heavy Metal (Pb) | ≤10ppm | Qualified |
Arsenic (As) | ≤2ppm | Qualified |
Residue on Ignition | ≤0.1% | 0.02% |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of cosmetic grade Hexamidine Diisethionate?
A1: The standard MOQ is 1KG, and sample orders are supported for formula testing and stability trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS and full set of global customs clearance documents are available to support export declaration and cosmetic filing.
• Q3: What is the recommended dosage in skin care and scalp formulas?
A3: Conventional addition ratio is 0.05%-0.2% for daily antibacterial soothing care, 0.2%-0.5% for high-efficiency anti-dandruff and anti-acne products, adjustable according to efficacy demands.
• Q4: What is the core advantage of Hexamidine Diisethionate compared with traditional antibacterial ingredients?
A4: It features mild safety, broad-spectrum bacteriostasis, no drug resistance, dual efficacy of anti-inflammation and oil control, avoids irritation and dryness of traditional antibacterial agents, and is suitable for long-term use.
• Q5: What ingredients is Hexamidine Diisethionate suitable for compounding?
A5: It can be perfectly compounded with salicylic acid, zinc pyrithione, centella extract, niacinamide and soothing ingredients to build multi-dimensional anti-dandruff, anti-acne and soothing repair system.
• Q6: Do you support stable large-batch supply all year round?
A6: Sufficient factory production capacity ensures continuous, stable and large-volume supply throughout the year to support long-term cooperative orders and customized formula demands.
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